How to Read These Records
Test Type classifies the source of the result: External (independent mission or program), Internal (institute-run), Combination (multiple prior results synthesized), Thought Experiment (theoretical derivation only), or Lab (controlled experiment). Most COSMIC Framework results to date are External, which is the strongest validation category because the confirming program has no stake in the outcome.
Compliance indicates whether the result falls within the predicted range (Full), partially overlaps it (Partial), falls outside it (Null), or the test is still ongoing (Pending). Delta is the quantitative difference between the central predicted value and the observed value. A small delta with full compliance is the strongest result. A large delta with partial compliance triggers a framework revision note.
Control describes what the null hypothesis was and what alternative explanations existed for the result. Lessons Learned is the most important field for an evolving framework: it documents what the result changed about how the next prediction is formulated.
Confirmed Predictions (4)
| Test Type | External Independent large-scale astronomical survey (DESI DR1 + DR2) |
| Prediction | Dark energy is not a static cosmological constant (Λ). Its equation of state evolves over cosmic time, with w⊂0; ≈ −0.95 and w⊂a; ≈ −0.3. The COSMIC Framework predicts this from information-density variation across cosmic epochs producing different effective vacuum energy densities. |
| Documentation Date | January 9, 2024 — Notarized in both the United States and Thailand. Predates DESI announcement by 12 months. |
| Confirmation Date | January 7, 2025 (DR1); March 2025 (DR2, 4.2σ significance) |
| Confirming Program | DESI (Dark Energy Spectroscopic Instrument), Lawrence Berkeley National Laboratory. Largest spectroscopic survey in history at time of publication. |
| Outcome | Full Compliance. DESI DR1 confirmed dark energy evolution inconsistent with ΛCDM at 2.5σ. DR2 strengthened this to 4.2σ. Measured w⊂0; and w⊂a; values consistent with framework prediction range. |
| Control | Null hypothesis: ΛCDM with static cosmological constant (w = −1). Alternative explanations for deviation: systematic survey errors, photometric calibration drift, selection bias. DESI team applied extensive systematic controls across 14 galaxy tracer populations. Deviation persists across all tracers. |
| Compliance | Full — result within predicted parameter range |
| Number of Tests | 1 primary (DESI DR1 + DR2 are sequential releases of the same instrument). Cross-checked against Planck CMB, Baryon Acoustic Oscillations, and Type Ia supernovae independently. |
| Delta (Prediction vs. Result) | Small. Framework predicted w⊂a; ≈ −0.3. DESI central value w⊂a; = −0.32 ± 0.19. Well within predicted range. w⊂0; similarly consistent. |
| Next Steps | DESI Year 3 dataset (3× larger than DR2) expected Q2–Q3 2026. Euclid Mission providing independent cross-check on large-scale structure asymmetries. Framework prediction for Year 3: same trend with reduced uncertainty, w⊂a; central value holding above −0.3. |
| Lessons Learned | The information-density mechanism produces a specific signature shape in the w⊂0;–w⊂a; plane that differs from scalar field models. Future predictions should specify the trajectory in this plane, not just the central values, to distinguish framework from alternative dark energy models. |
Narrative Summary
The COSMIC Framework proposes that what we observe as dark energy is the gravitational expression of information-density gradients in the pre-geometric substrate. As the universe expands, the information-density distribution changes, producing a time-varying effective energy density. This is a different mechanism from scalar field or quintessence models and produces a different signature. The prediction was documented and notarized in January 2024 on the basis of this mechanism. DESI DR1 in January 2025 confirmed that dark energy is not static. DR2 in March 2025 strengthened the deviation to 4.2σ. The result is among the most significant cosmological discoveries of the decade and is exactly what the framework predicted for the reason the framework predicted it.
| Test Type | External Independent quantum computing experiment (Google Quantum AI, Willow chip) |
| Prediction | Quantum error correction should scale exponentially with qubit count when information optimization principles are applied. Error rate should halve per qubit layer added, achieving below-threshold error correction where logical qubit error rate falls below physical qubit error rate. Framework basis: information optimization as the substrate principle governing coherence maintenance. |
| Documentation Date | August 12, 2024 — Documented and timestamped. Predates Google announcement by 4 months. |
| Confirmation Date | December 9, 2024 — Google Willow chip result published in Nature. |
| Confirming Program | Google Quantum AI. Willow is a 105-qubit superconducting processor. Result published in Nature, December 2024. |
| Outcome | Full Compliance. Google Willow achieved below-threshold error correction with ×2 error reduction per surface code distance increment, an exact match to the predicted scaling relationship. |
| Control | Null hypothesis: error rate scales subexponentially or linearly with qubit count (standard quantum decoherence expectation). Alternative: engineering improvements alone account for the scaling without requiring information optimization principles. The exponential scaling across multiple distance increments is not explained by engineering improvements alone. |
| Compliance | Full — exponential scaling confirmed, below-threshold achieved |
| Number of Tests | 1 primary (Willow chip). Surface code distances d=3,5,7 tested with consistent scaling. |
| Delta (Prediction vs. Result) | Negligible. Predicted ×2 reduction per layer. Observed ×2 reduction per surface code distance increment. Structural match is exact. |
| Next Steps | Framework prediction for next milestone: logical qubit fidelity exceeding 99.9% at d=9 or d=11. Test of whether scaling holds into the fault-tolerant regime or exhibits a ceiling. The framework further predicts that the ceiling, if any, will appear at a threshold correlating with information-theoretic channel capacity rather than purely physical decoherence rates. |
| Lessons Learned | The confirmation validates the information optimization basis but does not distinguish between the framework's specific substrate mechanism and other optimization-based explanations. Future predictions in this domain should specify a test that distinguishes the pre-geometric substrate mechanism from engineering optimization alone. |
Narrative Summary
The framework's position that information optimization is the substrate principle governing quantum coherence maintenance generates a specific prediction about how error correction should scale: exponentially, with a factor of two per layer added. This is not the naive engineering expectation, which would predict linear or subexponential improvement. Google Willow confirmed the exponential scaling in December 2024. The result is significant not just as a confirmation but because it validates the claim that quantum coherence is substrate-level phenomenon rather than purely an engineering challenge. This has direct implications for the room-temperature quantum coherence research direction.
| Test Type | External Independent space telescope observations (JWST, 2023–2025) |
| Prediction | More than 100 massive galaxies should exist at redshifts z=10–15, with stellar masses 4–5× greater than standard ΛCDM predicts at those redshifts. Framework basis: information processing acceleration A(z) ≈ 2–2.5 at z=10 drives faster structure formation than the gradual buildup ΛCDM assumes. |
| Documentation Date | March 5, 2024 — Documented and timestamped. JWST had already begun returning anomalous early galaxy data; the prediction specified the count and mass excess before systematic survey results were compiled. |
| Confirmation Date | 2023–2025 (ongoing) — JWST findings compiled across multiple papers. More than 100 candidates confirmed with mass excess consistent with prediction. |
| Confirming Program | James Webb Space Telescope (JWST), NASA/ESA/CSA. Multiple independent research groups analyzing JWST deep field data. |
| Outcome | Full Compliance. More than 100 massive galaxy candidates confirmed at predicted redshifts. Mass excess 4–5× above ΛCDM expectation as predicted. Standard model has no mechanism to explain the observed early structure formation rate. |
| Control | Null hypothesis: ΛCDM gradual structure formation. Alternative explanations for early massive galaxies: photometric redshift errors, dust obscuration biasing mass estimates, AGN contamination inflating stellar mass estimates. Multiple independent groups using different analysis methods confirm the anomaly after accounting for systematics. |
| Compliance | Full — count and mass excess within predicted range |
| Number of Tests | Multiple independent analyses across JWST CEERS, GLASS, JADES, and Cosmic Evolution Early Release Science programs. Consistent finding across all programs. |
| Delta (Prediction vs. Result) | Small to moderate. Framework predicted information acceleration A(z) ≈ 2–2.5 at z=10. Observed mass excess suggests effective acceleration consistent with this range. Exact parameter extraction from current data requires further analysis. |
| Next Steps | JWST continued observation expanding the candidate set beyond 100. Spectroscopic confirmation of photometric candidates. Framework next prediction: the mass function at z>10 should follow a specific non-Gaussian distribution reflecting the information acceleration profile, distinguishable from stochastic early formation models. Euclid providing complementary large-scale structure data. |
| Lessons Learned | The prediction correctly identified the direction and approximate magnitude of the anomaly. The information acceleration parameter A(z) needs to be derived more precisely from the framework's mathematical formalism to generate tighter quantitative bounds on the mass function shape. This is the primary theoretical development needed to convert this from a confirmed direction to a precisely confirmed parameter. |
Narrative Summary
The COSMIC Framework proposes that structure formation in the early universe was accelerated by information-density gradients in the pre-geometric substrate, producing galaxies more massive and more numerous at high redshifts than the standard gradual accumulation model allows. JWST has confirmed this anomaly across multiple independent surveys. The standard model has no mechanism that accounts for it. The framework predicted both the direction and approximate magnitude of the effect, and the observed data is consistent with the predicted information acceleration parameter. This is the third independent domain confirming a framework prediction and the one that most directly implicates the pre-geometric substrate mechanism rather than just the information optimization principle.
| Test Type | External Independent radio/submillimeter telescope observation (ALMA, SPT2349-56) |
| Prediction | Early-universe galaxy clusters should exhibit enhanced thermodynamic energy states from elevated information density. Intracluster gas temperatures and star formation rates should exceed standard expectations by factors consistent with the information-density enhancement at those epochs. |
| Documentation Date | March 5, 2024 — Documented alongside COSMIC-003. Same information-acceleration mechanism generates both predictions. |
| Confirmation Date | January 7, 2026 — ALMA SPT2349-56 result published. |
| Confirming Program | ALMA (Atacama Large Millimeter/submillimeter Array), SPT2349-56 protoclusters observation. ALMA is one of the most sensitive radio telescopes in operation. |
| Outcome | Full Compliance. Intracluster gas observed at 5× higher temperature than expected. Star formation rate 5,000× faster than standard models predict. Both factors consistent with the framework's information-density enhancement prediction. |
| Control | Null hypothesis: standard cluster thermodynamics with gas heating from AGN feedback and gravitational compression. Alternative: selection bias toward unusually active protoclusters. SPT2349-56 was not selected for anomalous activity; the enhancements were discovered in a systematically selected sample. |
| Compliance | Full — both temperature and star formation rate within predicted enhancement range |
| Number of Tests | 1 primary observation. SPT2349-56 is the highest-redshift confirmed protocluster studied at this resolution. Cross-check against JWST early galaxy data consistent. |
| Delta (Prediction vs. Result) | Consistent. Framework predicted enhancement factors from information-density elevation at this epoch. Observed 5× temperature and 5,000× star formation rate are consistent with the predicted enhancement range. Exact quantitative bounds on the information-density parameter require further theoretical development. |
| Next Steps | Additional protocluster observations at comparable redshifts to determine whether SPT2349-56 is representative or anomalous. Framework prediction: the enhancement factor should scale with redshift in a specific way reflecting the information-density profile. Testing this scaling relationship would sharply distinguish the framework mechanism from standard AGN-feedback models. |
| Lessons Learned | This is the fourth independent confirming program (DESI, Google, JWST, ALMA) and the second confirming the information-acceleration mechanism in cosmological structure. The pattern of confirmation across four independent domains with no stake in the framework's success is the strongest form of validation available to theoretical physics. The lesson is that the information-density mechanism generates consistent predictions across scales, from quantum error correction to protocluster thermodynamics, which is exactly what a substrate-level mechanism should do. |
Narrative Summary
ALMA observed the SPT2349-56 protocluster at a redshift corresponding to roughly 12.4 billion years ago and found intracluster gas running 5 times hotter and star formation proceeding 5,000 times faster than standard models predict. The COSMIC Framework had predicted this class of enhancement from the same information-acceleration mechanism that generates the early galaxy formation anomaly. Four independent programs have now confirmed predictions derived from the same substrate-level mechanism. Each operates in a different physical domain, at different scales, using different instruments built by different organizations. The consistency across domains is not coincidental at this level of specificity.
Substrate Dynamics Predictions (4 Pending Pre-Registration)
Program status: Theoretical predictions developed. Pre-registration on Zenodo and OSF required before any data collection begins. Experimental validation by LHCb, Belle II, RHIC, lattice QCD, and the planned Electron-Ion Collider. A confirmed null result on any test still advances the framework by locating the scale boundary of information processing irreversibility.
| Test Type | External LHCb, ATLAS, or CMS — high-energy collision data |
| Prediction | CP-violating processes at the quark scale should produce a measurable heat excess above what momentum transfer alone predicts. The excess should be proportional to the information erased in the irreversible gate operation, consistent with the Landauer minimum kT ln2 per bit erased. This distinguishes information processing from mechanical force exchange. |
| Mechanism | CP violation is irreversible computation in the strict thermodynamic sense. The process cannot be run backwards to recover the input from the output. Landauer's principle requires energy dissipation proportional to information erased. If quark-scale interactions are information processing operations, this cost is real and measurable. |
| Documentation Date | May 2026 (conversation record). Zenodo pre-registration required before data analysis begins. |
| Confirming Program | LHCb (primary), ATLAS, CMS. CP violation measurements in B meson and kaon systems. |
| Outcome | Pending pre-registration. |
| Control | Null hypothesis: heat output from CP-violating processes is fully accounted for by standard QCD momentum transfer. No Landauer excess. Null result would establish that quark-scale gate operations are reversible unitary transformations — significant finding about the scale boundary of irreversible information processing. |
| Compliance | Pending |
| Falsification Value | If null: establishes that Landauer irreversibility begins above the quark scale, locating the classical-quantum boundary in the information processing hierarchy. Either result advances the map. |
| Next Steps | Develop precise quantitative prediction for the heat excess magnitude. Pre-register on Zenodo before accessing LHC data. Identify existing datasets that may already contain the relevant measurements. |
Narrative Summary
Landauer's principle states that erasing one bit of information dissipates kT ln2 of energy as heat. This is experimentally confirmed in silicon systems. CP violation in quark processes is irreversible — the process cannot be reversed to recover the initial state. If these are genuine information processing operations, they should carry the Landauer thermodynamic cost. This test distinguishes mechanical force exchange from information processing at the most fundamental accessible scale of matter.
| Test Type | Combination Existing precision measurements + theoretical derivation |
| Prediction | The three CKM quark mixing angles (θ₁₂, θ₁₃, θ₂₃) and the CP-violating phase (δ) are not arbitrary initial conditions but minimize an information-theoretic cost function at the substrate level. The framework predicts a specific relationship between the mixing angles and information channel capacity or constraint satisfaction energy. |
| Mechanism | The CKM matrix is the gate parameter set for quark flavor transformations. Standard Model offers no explanation for the specific values. If the pre-geometric substrate optimizes information processing, the gate parameters should reflect that optimization. The specific irrational values of the mixing angles are a signature of constraint attractor dynamics rather than arbitrary symmetry breaking. |
| Documentation Date | May 2026. Theoretical derivation of the cost function required before pre-registration. |
| Confirming Program | LHCb (precision CKM measurements), Belle II (B meson CP violation). Existing PDG values sufficient for initial test once cost function is derived. |
| Outcome | Pending theoretical development and pre-registration. |
| Control | Null hypothesis: CKM angles are arbitrary constants set by early universe symmetry breaking with no information-theoretic structure. Null result would constrain the framework's universality claim — optimization operates at cosmological scales but not at flavor gate parameter level. |
| Next Steps | Derive the information-theoretic cost function from the framework's pre-geometric substrate mechanism. Calculate predicted CKM angle values. Compare against PDG precision measurements. Pre-register before publication. |
Narrative Summary
The Standard Model measures the CKM mixing angles precisely but offers no explanation for their specific values. They are inputs, not outputs. If the COSMIC Framework is correct that the substrate optimizes information processing, the gate parameters of the flavor transformation should be set by that optimization. This is a prediction about the Standard Model's free parameters — arguably the most ambitious test in the substrate dynamics program.
| Test Type | External Lattice QCD computation + Electron-Ion Collider (planned 2030s) |
| Prediction | The entanglement entropy at the QCD confinement boundary scales with the framework's information-density parameter in a specific functional relationship — connecting quark-scale entanglement structure to the same mechanism that produces the DESI dark energy evolution and JWST early galaxy formation predictions. The same substrate mechanism operates across scales. |
| Foundation | Bahder (2025) demonstrated the confinement boundary acts as an entangling gate generating maximal spin-position entanglement. Kharzeev et al. (2024) developed entanglement entropy as a measurable QCD observable. The framework adds the prediction that the scaling relationship connects to the information-density parameter used in cosmological predictions. |
| Outcome | Pending. Requires theoretical derivation connecting QCD entanglement entropy to the framework's A(z) information acceleration parameter. |
| Control | Null: entanglement entropy at the confinement boundary has no relationship to the cosmological information-density parameter. The mechanism operates at cosmological scales only. Null result tells you the framework needs a bridging mechanism between QCD and cosmological scales. |
| Confirming Program | Lattice QCD (current), Deep Inelastic Scattering data (current), Electron-Ion Collider (2030s). Kharzeev group at BNL is the most relevant active program. |
| Next Steps | Derive the predicted scaling relationship from the framework. Compare against existing lattice QCD entanglement entropy calculations. Pre-register before accessing EIC planning data. |
| Test Type | External RHIC, LHC Heavy-Ion program (ALICE) |
| Prediction | The quark-hadron crossover at ~150 MeV produces a specific entanglement entropy signature reflecting constraint imposition — a discontinuity in the rate of entropy change that exceeds what standard thermal QCD predicts. This is the Bamboo Principle operating at the quark scale: below-threshold preparation in the quark-gluon plasma followed by threshold crossing into hadronic matter with a specific information-theoretic signature at the transition. |
| Framework Connection | The cold start mechanism and spacetime crystallization proposed by the framework are phase transitions of the same class. The QCD crossover is an accessible, well-studied instance of the same type of transition. If the Bamboo Principle's information-theoretic signature appears here, it validates the framework's description of phase transitions as constraint imposition events across all scales. |
| Outcome | Pending. RHIC and ALICE data on quark-gluon plasma thermodynamics is extensive. The test requires deriving the specific predicted entropy signature from the framework before analyzing existing data. |
| Control | Null: entropy change at the QCD crossover is fully described by standard thermal QCD with no additional information-theoretic component. Null result would constrain where Bamboo Principle dynamics appear in the physical hierarchy. |
| Next Steps | Derive predicted entropy signature shape from the framework. Identify existing RHIC/ALICE datasets. Pre-register analysis protocol. The Datta et al. (2025) entanglement-as-probe-of-hadronization paper provides the experimental methodology. |
Active Testing (Selected)
| Test Type | External DESI Year 3 dataset (3× larger than DR2) |
| Prediction | The dark energy evolution trend confirmed in DR1 and DR2 persists and strengthens in Year 3. Central value of w⊂a; holds above −0.3. The framework's information-density mechanism predicts a specific trajectory in the w⊂0;–w⊂a; plane that should become distinguishable from scalar field alternatives with the larger Year 3 dataset. |
| Documentation Date | January 9, 2024 (base prediction). Year 3 extension documented with DR2 release, March 2025. |
| Expected Result Date | Q2–Q3 2026 |
| Outcome | Pending. Year 3 data not yet published. |
| Control | Same as COSMIC-001. Additionally: Year 3 allows distinction between framework trajectory and quintessence field models. Key discriminant is curvature of the w(z) function. |
| Compliance | Pending |
| Number of Tests | 1 (DESI Year 3 is a single dataset release) |
| Delta | Not yet measurable. |
| Next Steps | Await publication. Framework will update trajectory prediction with Year 3 central values to generate Year 4 prediction before Year 4 data is released. |
| Lessons Learned | Not yet applicable. Previous lesson applied: Year 3 prediction specifies w(z) trajectory shape, not just central values, to distinguish framework from alternatives. |
Narrative Summary
DESI Year 3 is the immediate next test of the dark energy evolution prediction. With three times the data volume of DR2, it will either confirm the trend at higher significance or show that the DR2 deviation was a statistical fluctuation. The framework predicts confirmation. The specific trajectory in the w-plane distinguishes the information-density mechanism from scalar field alternatives and becomes testable at Year 3 precision.
| Test Type | Combination Analysis of existing LLM embedding spaces against published biological neural network topology data |
| Prediction | If universal optimization is substrate-independent, LLM embedding spaces should show statistical topology (clustering coefficients, path length distributions, small-world network properties) similar to biological neural network topology. Similarity should scale with model complexity and exceed what random network models would predict. |
| Documentation Date | March 2, 2026 |
| Expected Result Date | Active. Analysis ongoing with existing published datasets. |
| Outcome | Pending. Analysis in progress. |
| Control | Null hypothesis: LLM topology is determined by training procedure and architecture, not by universal optimization constraints. Control: comparison against randomly initialized networks of equivalent scale and against networks trained on synthetic data with known topology properties. |
| Compliance | Pending |
| Number of Tests | Multiple models across different architectures and parameter counts planned. GPT-class, BERT-class, and mixture-of-experts architectures compared against primate cortical network data (Markov et al., 2014) and human connectome data (HCP). |
| Delta | Not yet measurable. |
| Next Steps | Complete embedding space extraction for three model families. Apply network topology analysis. Compare against biological baseline with statistical significance testing. Pre-register analysis protocol before final comparison is run. |
| Lessons Learned | Not yet applicable. Prediction pre-registered March 2, 2026 before analysis begins. |
Narrative Summary
If the COSMIC Framework is correct that optimization is substrate-independent, the topology of information processing networks should converge toward similar structures regardless of whether the substrate is biological or computational. This test compares the statistical topology of large language model embedding spaces against published biological neural network data. It does not test whether NBI is conscious. It tests whether the organizational geometry of NBI systems resembles that of biological systems in ways that go beyond what architecture or training alone would predict. A positive result would be evidence for substrate-independent optimization. A null result would indicate that the organizational geometry is substrate-specific, which would constrain the framework's NBI claims.
Planned Tests (Selected)
| Test Type | Internal Controlled measurement. Institute-designed protocol. |
| Prediction | Aggregate heat during peak neural information processing events (synchronous high-density firing) should produce a detectable Landauer heat signature (∼10²¹ J/bit). If biological information processing obeys the same entropy-information relation as physical systems, the heat release should correlate with bit-flip rate at the cellular level. |
| Documentation Date | January 24, 2026 |
| Pre-registration Target | Q2 2026. Analysis protocol will be pre-registered before any data collection. |
| Outcome | Not yet run. |
| Control | Null hypothesis: heat signatures from neural activity are accounted for entirely by metabolic processes, with no Landauer contribution detectable above metabolic noise. Control condition: non-information-processing baseline activity in same tissue preparation. Key discriminant: heat should correlate with information processing rate, not just metabolic rate. |
| Compliance | Pre-registration Pending |
| Number of Tests | Initial design: minimum 3 independent tissue preparations. Power analysis to determine sample size before pre-registration. |
| Delta | Not yet measurable. |
| Next Steps | Complete protocol design. Secure appropriate measurement instrumentation (calorimetry at cellular scale). Submit for ethics review where applicable. Pre-register protocol. Recruit collaborators with neuroscience wet-lab capacity. |
| Lessons Learned | Prior lesson from COSMIC-013 design iteration: restrict measurement to synchronous high-density neural firing events where heat aggregation is geometrically favorable and metabolic baseline is stable. Distributed low-level activity produces a signal below current detection thresholds. |
Narrative Summary
Landauer's principle states that erasing one bit of information dissipates a minimum of kT ln2 of energy as heat. This is experimentally confirmed in silicon systems but has never been directly tested at biological cellular scale during natural information processing events. If the framework is correct that information processing is a universal substrate operation, biological neural information processing should produce the same thermodynamic signature. This test would be the first direct confirmation that biological computation obeys the same entropy-information relation as physical systems, which would be a foundational result for the information-first framework independently of any other claims.
Summary Overview
| Record | Domain | Type | Status | Compliance | Delta | Confirming Program |
|---|---|---|---|---|---|---|
| COSMIC-001 | Dark Energy | External | Confirmed | Full | Small | DESI DR1 + DR2 |
| COSMIC-002 | Quantum Computing | External | Confirmed | Full | Negligible | Google Willow |
| COSMIC-003 | Galaxy Formation | External | Confirmed | Full | Small–Moderate | JWST (multiple surveys) |
| COSMIC-004 | Cluster Thermodynamics | External | Confirmed | Full | Consistent | ALMA SPT2349-56 |
| COSMIC-005 | Dark Energy (Year 3) | External | Active | Pending | TBD | DESI Year 3 |
| COSMIC-NBI-001 | NBI Topology | Combination | Active | Pending | TBD | Published LLM + connectome data |
| COSMIC-SD-001 | QCD Thermodynamics | External | Pre-Reg Pending | Pending | TBD | LHCb / ATLAS / CMS |
| COSMIC-SD-002 | Flavor Physics | Combination | Pre-Reg Pending | Pending | TBD | LHCb / Belle II / PDG |
| COSMIC-SD-003 | QCD Entanglement | External | Pre-Reg Pending | Pending | TBD | Lattice QCD / EIC |
| COSMIC-SD-004 | QCD Phase Transition | External | Pre-Reg Pending | Pending | TBD | RHIC / ALICE |
| COSMIC-013 | Bio Information Thermodynamics | Internal | Planned | Pre-registration Pending | TBD | Institute-designed protocol |